Margaret married Patrick (1st Earl of Bothwell) Hepburn about 21 Feb 1491. Patrick (son of Adam (Master of Hailes) Hepburn and Helen Home) died on 18 Oct 1508. [Group Sheet] [Family Chart]

Adam married Agnes (Countess of Bothwell) Stewart in 1511. Agnes (daughter of James (1st Earl of Buchan) Stewart and Margarett Murray) died in Feb 1556-1557. [Group Sheet] [Family Chart]

Family/Spouse: Nicholas Home. Nicholas (daughter of Alexander (3rd Lord) Home and Nichola Ker) and died. [Group Sheet] [Family Chart]

Notes:

He was a child when his father died . On 26th April 1531 he was appointed a Lord of the Articles but in December of that years he entered into treasonable correspondence with Henry VIII which upon being discovered he was imprisoned in Edinburgh castle. He was still there in July 1533. At the end of 1540 he was banished from the Kingdom. Following the death of King James V he returned and on 14th December 1542 he commenced proceedings which resulted in him regaining properties forfeited previously. It was rumoured that he was interested in marrying Mary of Lorraine, the Queen-Dowager, and doubtless in the hope of this union he procured a divorce from his wife before October 1543. His expectation was disappointed.
He again intrigued with the English, traitorously corresponded with the Earl of Hertford during the latter?us invasion of Scotland in 1544 and was summoned for treason in Parliament in November of that year. He nevertheless had a remission the following month. One of the charges against him was the acceptance of great gifts and money from Henry VIII. He was said to be heavily in debt at the time and this may account for his actions. Notwithstanding his remission he again underwent a term as State prisoner and was only released after the battle of Pinkie, which took place on 10th September 1547. He was subsequently deprived of his castle of Hailes and Earl Patrick promptly renounced his allegiance and adhered to England. Although again arraigned for treason he appears again to have been rehabilitated, as he died at Dumfries in September 1556 '?tLieutenant in the honourable service of the realm.?u
He married circa 1533 Agnes, daughter of Henry Lord Sinclair and his wife Margaret Hepburne, daughter of Adam Hepburn Master of Hailes. (see above). This lady, as already noted, was divorced by Earl Patrick before 16th October 1543, whereupon he settled on her a charter of the lands of Morham in Haddingtonshire. She was subsequently styled ?uThe Lady of Morham?u for the rest of her life. She died in 1572.

Patrick married Agnes Sinclair about 1534. Agnes (daughter of Henry (3rd Lord) Sinclair and Margaret (of Bothwell) Hepburn) died about 1574. [Group Sheet] [Family Chart]

James married Jean (of Huntly) Gordon on 24 Feb 1565-1566 in Annulment 1567. Jean (daughter of George (4th Earl of Huntly) Gordon and Elizabeth Keith) and died. [Group Sheet] [Family Chart]

James married Mary Queen of Scots on 15 May 1567 in Holyrood Palace, Edinburgh, Scotland. Mary (daughter of James V Stewart King of Scotland and Mary De Guise De Lorraine) was born on 7 Dec 1542 in Palace Of Linlithgow, West Lothian, Scotland; died on 8 Feb 1587 in Beheaded At Fotheringay Castle, Northampton; was buried in 1612 in Westminster Abbey. [Group Sheet] [Family Chart]

Family/Spouse: John (Prior of Coldinghame) Stewart. John (son of James V Stewart King of Scotland and Elizabeth (Katherine) Carmichael) was born about 1531; died in 1563. [Group Sheet] [Family Chart]

Family/Spouse: John (Master of Caithness) Sinclair. John (son of George (4th Earl of Caithness) Sinclair and Elizabeth (of Montrose) Graham) died about 1578. [Group Sheet] [Family Chart]

Notes:

Jane (also sometimes referred to as Joanna and Janet) Hepburne, frequently styled ?tMistress Bothwell?u. This lady received her mother?us inheritance of Morham. She married three times. First, on 28th December 1561?, to John Stewart, Commendator of Coldingham Abbey, later created Lord Darnley, a natural son of King James V by Katherine Carmichael. He died in October 1563.
Francis Stewart, the eldest son of this marriage, was created Earl of Bothwell by King James VI in consideration of his extraction on his mother?us side.
Jane married secondly,between 10th December 1565 and 16th January 1567, John Sinclair, Master of Caithness, eldest son of George 4th Earl of Caithness,who died about 1578. His widow married, thirdly, Rev. Archibald Douglas, Rector of Douglas and one of the Senators of the College of Justice. He was also brother to William Douglas of Whittinghame, a cadet of the house of Morton.
2 - John Stuart, the titular abbot of Coldingham, a natural son of James V., was importuned to join the Black Band, but had too much regard for Wedderburn to do so. While he was absent in the north with his brother the Regent Moray, his wife, who had a spite at Wedderburn, made a strange kind of demonstration against him. She ordered the men of her faction to be present on a certain day, and to bring along with them wains, carts, and other things fit for carrying off the corns, all of which was carefully done. But Wedderburn with his friends having gathered together about 500 horse, hastens to the fields, and dissipates the scattered troops before they could unite themselves into one, breaks the wagons, looses the horses, and drives them away. On this they all betake themselves to flight, together with Stuart?us wife (she was called Hepburn, and a sister of old Bothwell). A few received some strokes; none were wounded; but so great was the terror struck into them all, that they all sought hiding-places in their flight. Some hid themselves among the furze or broom; others under the banks of the river; some in the fields of corn, and all either in one place or other. One John Edington (commonly called the Liar, as he was always the messenger of strange news, which was commonly false) hid himself in the ambry of a poor old woman, from which he was dislodged, to the great diversion of his enemies and his own great terror. When their fear a little subsided, and it appeared that none were hurt, the affair appeared so ridiculous both to themselves and others, that Hepburn (as she was a woman of a pretty good genius and poetically inclined) described the whole in some verses. Nor was there ever anything afterwards attempted by the confederates.Source:http://www.electricscotland.com/history/domestic/vol1ch5.htm

Family/Spouse: Sir Archibald (of Whittinghame) Douglas. Archibald (son of William (2nd of Whittingham) Douglas and Janet Matheson) died before 1643. [Group Sheet] [Family Chart]