Cosimo II (Grand Duke of Tuscany) De Medici
1590 - 1621 (31 years)
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| Ferdinando II (Grand Duke of Tuscany) De Medici 1610-Yes, date unknown |
| Ferdinando II (Grand Duke of Tuscany) De Medici | |
| B: | 14 Jul 1610 |
| D: | Yes, date unknown |
| Odoardo II (Hereditary Prince of Parma) Farnese | |
| B: | 1666 |
| D: | 1693 |
 | Dorothea Sophie Von Neuburg 1670-1748 |
| Dorothea Sophie Von Neuburg | |
| B: | 1670 |
| M: | 17 Sep 1690 |
| D: | 1748 |
| Ranuccio II Duke of Parma And Piacenza 1630-1694 |
| Ranuccio II Duke of Parma And Piacenza | |
| B: | 17 Sep 1630 |
| D: | 1694 |
| Isabella D'este 1635-1666 |
| Isabella D'este | |
| B: | 1635 |
| M: | 18 Feb 1664 |
| D: | 17 Aug 1666 |
| Margherita De Medici 1612-1679 |
| Margherita De Medici | |
| B: | 31 May 1612 |
| D: | 1679 |
| Odoardo I Duke of Parma 1612-1646 |
| Odoardo I Duke of Parma | |
| B: | 28 Apr 1612 |
| M: | 1628 |
| D: | 1646 |
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| Cosimo II (Grand Duke of Tuscany) De Medici | |
| B: | 1590 |
| D: | 28 Feb 1621 |
| Marie-Madeleine of Austria 1589-1631 |
| Marie-Madeleine of Austria | |
| B: | 1589 |
| M: | 19 Oct 1608 |
| D: | 1631 |