Isabella married Charles Stryker Little on 20 Sep 1838 in Newburgh, Orange Co., NY. Charles (son of John Little and Sarah "Sally" Deziah Case) was born on 1 Jun 1813 in Chester, Town Of Goshen, Orange Co., NY; died on 22 Oct 1872 in Brooklyn, NY. [Group Sheet] [Family Chart]

1. John Forsyth Little was born on 27 Jul 1839 in New York, NY; died on 9 May 1842 in New York , NY.
2. Jane Ann Little was born on 23 Nov 1841 in New York, NY.
3. Robert Forsyth Little, Sr. was born on 11 Feb 1844 in NY, NY (Sunday); died on 3 Sep 1902 in Monticello, NY.
4. William Seely Little, M. D. was born on 17 Dec 1849 in New York, NY; died on 17 Feb 1887 in Aiken, SC.
5. Charles Edward Little was born on 6 Jul 1851 in New York , NY; and died.